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glutaminase c allosteric

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  • Inhibitors & Agonists
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Glutaminase C-IN-1
Compound 968, Glutaminase Inhibitor Compound 968
T3964311795-38-7
Glutaminase C-IN-1 (Compound 968) is an allosteric inhibitor of Glutaminase C (GLS1).
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Glutaminase C-IN-2
T78892
Glutaminase C-IN-2 (compound 11), an allosteric inhibitor of glutaminase C (GAC), shows potent inhibitory activity with an IC50 of 10.64 nM. By disrupting glutamine metabolism, it modulates cellular metabolites and elevates reactive oxygen species (ROS), exerting anticancer effects [1].
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