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gepotidacin hydrochloride

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  • Inhibitors & Agonists
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Gepotidacin hydrochloride
T714901075235-46-9
Gepotidacin hydrochloride, also known as GSK-2140944 hydrochloride, is a potent Type II DNA topoisomerase inhibitor. Gepotidacin hydrochloride is a novel antibacterial drug candidate. Gepotidacin hydrochloride Demonstrates Absence of Fluoroquinolone-Like Arthropathy in Juvenile Rats. Gepotidacin hydrochloride is efficacious in a nonhuman primate model of pneumonic plague. When tested against Gram-negative (n = 333) and Gram-positive (n = 225) anaerobes by agar dilution, Gepotidacin hydrochloride inhibited 90% of isolates at concentrations of 4 and 2 μg mL, respectively.
  • $3,320
10-14 weeks
Size
QTY
CM-546
T703571624792-73-9
CM-546 is the trans-isomer of CM-414, and a dual inhibitor of PDE5 and HDACs.
  • $1,520
6-8 weeks
Size
QTY
Gepotidacin mesylate dihydrate
GSK2140944 mesylate dihydrate, GSK-2140944 mesylate dihydrate, GSK 2140944 mesylate dihydrate
T703581624306-20-2
Gepotidacin mesylate dihydrate (GSK2140944 mesylate dihydrate) is an orally available triazaacenaphthylene antibiotic with antibacterial activity. Gepotidacin mesylate dihydrate is an inhibitor of bacterial type II topoisomerase. Gepotidacin mesylate dihydrate inhibits bacterial DNA replication by blocking topoisomerase and can be used to study bacterial infection.
  • $108
In Stock
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