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gdc-0152

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
GDC-0152
GDC0152
T6299873652-48-3
GDC-0152 is a potent inhibitor of IAPs.
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GDC-0152-acetamide
T212179
GDC-0152-acetamide is a pan-antagonist of apoptosis inhibiting proteins (IAPs). It induces the autoubiquitination and subsequent degradation of cIAP1/2, activates the non-canonical NF-κB pathway, and promotes the secretion of TNF-α, leading to apoptosis in tumor cells. GDC-0152-acetamide holds potential for research in ERα-positive breast cancer.
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