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gcn2 in 6

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
GCN2-IN-6
T113742183470-09-7In house
GCN2-IN-6 is also a eIF2α kinase PERK inhibitor with an IC50 of 0.26 nM (in enzymatic assay) and 230 nM (in cells). GCN2-IN-6  is a potent, and orally available GCN2 inhibitor confirmed by in-house enzymatic (IC50 of 1.8 nM) and cellular assays (IC50 of 9
  • $117
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AMG PERK 44
T102991883548-84-2In house
AMG PERK 44 is an orally active and selective PERK inhibitor (IC50: 6 nM) that induces autophagy. It also inhibits GCN2 (IC50: 7300 nM) and B-Raf (IC50 >1000 nM), making it useful for cancer research.
  • $65
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