gastritis

Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.

Troxipide (Aplace), a new-type systemic non-antisecretory gastric cytoprotective agent, which is mucus-secreting, anti-ulcer, and anti-inflammatory properties irrespective of pH of stomach or duodenum.

Cetraxate hydrochloride (DV10062) is an oral gastrointestinal medication. It has a cytoprotective effect.

2-Chlorophenylboronic acid is a monohalogenated phenylboronic acid, which is an important pharmaceutical intermediate and is widely used in the synthesis of new drugs.2-Chlorophenylboronic acid has an inhibitory effect on fatty acid amidase with a Ki value of 0.01-1 µM, and is used in the study of depression, glaucoma, neuropathic pain, anxiety, migraine, I diabetes and gastritis. , migraine, type I diabetes and gastritis.

DL-Methionine Methylsulfonium Chloride is a natural product, used in the treatment of peptic ulcers, colitis, and gastritis.

Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.

BE-18591 is a novel H+/Cl− co-transport ion carrier that exhibits inhibitory effects on immune proliferation and gastritis.

Butinoline (also known as azulone) was once utilized as an antispasmodic compound for the treatment of gastritis.

Urease-IN-12 (compound 5e) is a competitive urease inhibitor with an IC50 of 0.35 μM, showing potential in inhibiting gastritis and peptic ulcers caused by Helicobacter pylori.

Urease-IN-13 (compound d8) is a urease inhibitor with an IC50 value of 1.21 μM. It is utilized in research related to infectious gastritis and gastric ulcers.

Methantheline Bromide is a synthetic spasmolytic used to relieve cramps or spasms of the stomach, bowel, and bladder. It is also useful for intestinal or gastric ulcers (peptic ulcer disease), intestinal problems, pancreatitis, gastritis, biliary dysmotil

Urease-IN-11 (Compound 6e), with an IC50 of 10.41 µM, serves as a competitive inhibitor of urease. This compound is useful in researching diseases like urease-related gastritis and peptic ulcer [1].

Pseudotropine (Standard) is a reference standard for research and analysis in studies involving Pseudotropine. Pseudotropine can cause hepatic necrosis and gastritis with ulceration or erosions.

Dangshen polysaccharide is derived from the Codonopsis pilosula plant and exerts anti-inflammatory effects in treating gastric ulcers, gastritis, and gastric cancer by targeting the PI3K-AKT pathway and HIF-1 pathway.