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f368

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Dantrolene
T84527261-97-4
Dantrolene is a postsynaptic muscle relaxant by inhibiting Ca2+ ions release from sarcoplasmic reticulum stores by antagonizing ryanodine receptors.
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WF 3681
T12396690055-27-9
WF 3681 is a natural product that can be used as a reference standard. The CAS number of WF 3681 is 90055-27-9.
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Dantrolene-13C3
TMID-06561185234-99-4
Dantrolene-13C3 is the 13C3-labeled form of Dantrolene. Dantrolene (F368) serves as a muscle relaxant and non-competitively inhibits human erythrocyte glutathione reductase (glutathione reductase), exhibiting Ki and IC50 values of 111.6 μM and 52.3 μM, respectively. Additionally, Dantrolene acts as a ryanodine receptor antagonist and a stabilizer of Ca2+ signals. It is utilized in the treatment of muscle spasms and malignant hyperthermia.
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