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(2)
By Target- ALK
- c-Met/HGFR(2)
- Trk receptor(1)
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By Target By ResearchField- Cancer(2)
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Results for "
ensartinib
" in TargetMol Product Catalog- Inhibitors & Agonists2
Ensartinib hydrochloride
X-396 dihydrochloride, Ensartinib dihydrochloride
T223242137030-98-7
Ensartinib hydrochloride (X-396 dihydrochloride) is a potent new-generation ALK inhibitor with high activity against CNS metastases and a broad range of known crizotinib-resistant ALK mutations. It potently inhibits both wild-type ALK and ALK variants (C1156Y, F1174, G1202R, L1196M, S1206R, and T1151 mutants) with in vitro IC50s of <4 nM.
- $52
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QTY
Ensartinib
Cited
X-396, X396, Ensacove
T375851370651-20-9
Ensartinib (X-396) is a potent and orally active dual ALK/MET inhibitor for the treatment of ALK-positive non-small cell lung cancer (NSCLC).
- $52
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