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  • Estrogen Receptor/ERR
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em652

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Acolbifene
EM-652, SCH 57068
T10239182167-02-8In house
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
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6-8 weeks
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(Rac)-Acolbifene
(Rac)-EM-652, EM-343
T12654151533-34-5In house
(Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profile,relative binding affinity (RBA)=380.
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6-8 weeks
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