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  • Estrogen Receptor/ERR
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Results for "

em 652

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    4
    TargetMol | Inhibitors_Agonists
Acolbifene
EM-652, SCH 57068
T10239182167-02-8In house
Acolbifene (SCH 57068) is a selective antagonist of estrogen receptors with IC50s of 2 nM and 0.4 nM for estradiol-induced transcriptional activity of ERα and ERβ. Acolbifene shows an anticarcinogenic property.
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6-8 weeks
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(Rac)-Acolbifene
(Rac)-EM-652, EM-343
T12654151533-34-5In house
(Rac)-Acolbifene (EM-343) is the racemic form of Acolbifene. Acolbifene is a estrogen receptor antagonist. (Rac)-Acolbifene exhibits anti-estrogenic and estrogenic activities. (Rac)-Acolbifene contains a piperidine ring and exhibits good pharmacological profile,relative binding affinity (RBA)=380.
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6-8 weeks
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EM-651
2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-
T60115182167-58-4In house
EM-651 (2H-1-Benzopyran-7-ol, 3-(4-hydroxyphenyl)-4-methyl-2-[4-[2-(1-piperidinyl)ethoxy]phenyl]-, (2R)-) is an enantiomer of EM-652, IC50=20.0 nM. EM-652 is an orally active pure antiestrogen and selective estrogen receptor antagonist, IC50=0.44nM.
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EM-800
EM800,EM 800
T25367182167-03-9
EM-800 is a high affinity ligand for estrogen receptor-α (ERα), the prodrug of EM-652. EM-800 independently inhibited the growth of E1-stimulated ZR-75-1 xenograft tumors in nude mice.
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6-8 weeks
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