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eif2ak3/perk

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  • Inhibitors & Agonists
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    TargetMol | Antibody_Products
CCT020312
T14902324759-76-4In house
CCT020312 (0-9 µM, 24 h) treatment of medium HT29 cells for 24 h resulted in a concentration-dependent loss of P-S608-pRB signaling with linear response values between 1.8 and 6.1 µM.
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6-8 weeks
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GSK2606414
T26141337531-36-8
GSK2606414 is a cell-permeable and orally active protein kinase R-like endoplasmic reticulum kinase(PERK)inhibitor with IC50 of 0.4 nM. GSK2606414 inhibits PERK activation in cells and suppresses the growth of human tumor xenografts in mice.
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