e-1

Estrone (Aquacrine) is an aromatized C18 steroid with a 3-hydroxyl group and a 17-ketone, a major mammalian estrogen. It is converted from ANDROSTENEDIONE directly, or from TESTOSTERONE via ESTRADIOL. In humans, it is produced primarily by the cyclic ovaries, PLACENTA, and the ADIPOSE TISSUE of men and postmenopausal women.

Cangorinine E-1 (compound 11), a dihydroagarofuran sesquiterpenoid derivative, exhibits weak inhibitory effects on herpes simplex virus type II (HSV) [1].

Sphingosine-1-phosphate (S1P) is an agonist for S1P1-5 receptors and a ligand for GPR3, GPR6, and GPR12. As an intracellular second messenger, it mobilizes Ca2+ and acts as an extracellular ligand for G-protein coupled receptors. This important lipid mediator is generated from sphingosine or other membrane phospholipids.

1-Aminocyclopropane-1-carboxylic acid (ACC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. It is a small molecule agonist at the glycine modulatory site of the NMDA receptor (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate.2 This compound has been reported to protect against neuron cell death in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.

trans-Cyclohexane-1,2-diol (trans-1,2-Cyclohexanediol) has a synergistic retardation effect on percutaneous absorption and penetration of metronidazole (MTZ).

1-Phenylpropane-1,2-dione (Acetyl benzoyl) is a eukaryotic metabolite produced in plant metabolic reactions.

Docosane-1,22-diol (1,22-Docosanediol) is a long-chain fatty acid used in the synthesis of crystalline compounds.

2,5-dimethoxycyclohexa-2,5-diene-1,4-dio (Thermophillin) is a natural product. The redox cycle of 2,5-dimethoxybenzoquinone is a source of reducing equivalent for the regeneration of Fe2+ and H2O2 in brown rot fungal decay of wood.

Phenazine-1-carboxylic acid shows strong antifungal activity against all phytopathogenic fungi, inhibiting the fungal growth by about 90-100%. Phenazine-1-carboxylic acid could be used to compete with other phytopathogenic fungi that attack grapevine

2,4,6-tribromobenzene-1,3,5-triol (1,3,5-Benzenetriol, 2,4,6-tribromo-) is a marine derived natural products found in Rhabdonia verticillata.

2-Methylcyclohexa-2,5-diene-1,4-dione exhibits inhibitory activity against cancer cells such as A2780, HT-29, HL-60, and K562 (IC50 = 2.8–12.1 µM) and antibacterial activity against Bacillus subtilis.

Propane-1,2,3-triol (Glycerol) is commonly used as a solvent, softener, and moisturiser, and is widely applied in biochemical experiments and drug synthesis research.

4-Nitrobenzene-1,2-diol （4-Nitrocatechol） is a benzene derivative that is biologically active as an inhibitor of various enzymes.

Propane-1,2,3-triyl tripalmitate (Glycerol Tripalmitate) is a triacylglycerol found in dietary fats. In hamsters fed a diet enriched with it, Tripalmitin increases body weight, elevates plasma LDL levels, and reduces hepatic LDL receptor mRNA levels. It inhibits glucose-stimulated insulin secretion and decreases the viability of INS1 cells dose-dependently. Tripalmitin is used in cosmetic products for skin conditioning and as a thickening agent, and it forms lipid matrices of nanoparticles for drug delivery.

1,2,6,7,8,9-Hexahydro-1,6,6-trimethyl-3,11-dioxanaphth[2,1-e]azulene-10,12-dione, a chemical constituent of Salvia miltiorrhiza f. alba, is a dihydroisotanshinone featuring a para-quinone moiety with demonstrated cytotoxicity and anti-tumor activity [1] [2].

[(1(10)E,2R,4R)]-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one, a sesquiterpene from turmeric, is also known as (1(10)E,2R*,4R*)-2-Methoxy-8,12-epoxygermacra-1(10),7,11-trien-6-one.

1-O-Deacetyl-2alpha-hydroxykhayanolide E is a natural product of Swietenia, Meliaceae. The catalog number is TN2557 and the CAS number is 1189801-51-1. 1-O-Deacetyl-2alpha-hydroxykhayanolide E can be used as a reference standard.

1-O-Deacetylkhayanolide E, a natural product of Khaya (Meliaceae), is cataloged under TN2558 with a CAS number of 1007387-95-2 and can be used as a reference standard.

13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide is a natural product from Artemisia myriantha.

(E)-1-(4-Hydroxyphenyl)dec-1-en-3-one is a natural product for research related to life sciences. The catalog number is TN3905 and the CAS number is 958631-84-0.

(3S,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol has anti-oomycete potential.

(3R,5S,E)-1,7-Diphenylhept-1-ene-3,5-diol is a natural product for research related to life sciences. The catalog number is TN6486 and the CAS number is 232261-31-3.

(E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol is a natural product that can be used as a reference standard. The CAS number of (E)-1-methoxy-2-O-(p-coumaroyl)-myo-inositol is 1391715-18-6.

(E)-4-Methyl-5-styrylbenzene-1,3-diol (Compound III), sourced from Dracaena cochinchinensis (Lour.) S. C. Chen, serves as an antifungal agent [1].'