dspe-peg(2000)-azide

DSPE-PEG(2000)-azide is a PEGylated derivative based on 1,2-distearoyl-sn-glycero-3-phosphoethanolamine (1,2-DSPE). This compound is utilized for attaching vascular cell adhesion molecule-1 (VCAM-1) antibodies to vesicles that encapsulate fingolimod, aiming to target the delivery of fingolimod to inflammatory vessels in mouse models simulating post-ischemic neuroinflammation. Additionally, DSPE-PEG(2000)-azide is employed to link fibrinogen mimetic peptides (FMP) to the surface of synthetic platelets used in treating uncontrollable bleeding caused by liver damage in mouse models.

DSPE-PEG-Azide (MW 2000) has an amphiphilic structure and can form lipid bilayers micelles in water. It can be used to prepare nanoparticles or liposomes as targeted drug carriers.

DSPE-PEG-DBCO, MW 2000 is a phospholipid PEG polymer employed to create micelles used for drug delivery in the form of lipid nanoparticles. As a click chemistry reagent, DSPE-PEG-DBCO, MW 2000 contains a DBCO group that can react with molecules containing Azide groups to facilitate a strain-promoted alkyne-azide cycloaddition (SPAAC) reaction.

DSPE-PEG-DBCO, MW 2000, is a phospholipid PEG polymer that incorporates cyclooctyne. This polymer spontaneously self-assembles into micelles or lipid bilayers in aqueous solutions, making it suitable for nanoparticle or liposome preparation as drug carriers in targeted drug delivery systems. DBCO can react with azide molecules via copper-free click chemistry to form stable triazole bonds. Reagent-grade, for research use only.