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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T8372 | VU0134992 | VU 0134992 | Potassium Channel |
VU0134992 is an Kir4.1 blocker with an IC50 value of 0.97 μM | |||
T13316 | VU0134992 hydrochloride | Potassium Channel | |
VU0134992 hydrochloride is the first subtype-preferring, orally active and selective blocker of Kir4.1 potassium channel pore(IC50 : 0.97 µM). | |||
T1449 | Hydrochlorothiazide | HCTZ | Potassium Channel , Carbonic Anhydrase , TGF-beta/Smad |
Hydrochlorothiazide (HCTZ) is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis. | |||
T1484L | Perindopril erbumine | S9490-3,Perindopril tert-butylamine salt | Apoptosis , RAAS , MRP |
Perindopril erbumine (S9490-3) is the tert-butylamine salt of perindopril, the ethyl ester of a non-sulfhydryl angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. Upon hydrolysis, Perindopril er... | |||
T1083L | Theophylline monohydrate | Quibron | HDAC , PDE , Adenosine Receptor |
Theophylline monohydrate (Quibron) appears to inhibit phosphodiesterase and prostaglandin production, regulate calcium flux and intracellular calcium distribution, and antagonize adenosine. Theophylline monohydrate is a ... | |||
T70939 | 8-Aminoinosine | ||
8-Aminoinosine is an endogenous 8-aminopurine that induces diuresis, natriuresis, and glucosuria by inhibiting purine nucleoside phosphorylase (PNPase). | |||
T1400L | Demeclocycline | Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol | Antibacterial |
Demeclocycline (Declostatin) is a tetracycline antibiotic produced by a strain of Streptomyces aureofaciens.Demeclocycline has antimicrobial activity and inhibits the action of vasopressin on the renal tubules, leading t... | |||
T28313 | PD 117302 | PD-117302,PD117302 | |
PD 117302 is a nonpeptide opioid compound. It is a selective kappa-opioid agonist. PD 117302 causes naloxone-reversible locomotor impairment and diuresis. It is an Anti-Arrhythmia Agent, an Anticonvulsants, a Cardiovascu... | |||
T73218 | Epitizide | ||
Epitizide, a benzothiadiazine, commonly found in combination Triamterene , is used to produce diuresis [1] . | |||
T70250 | Demeclocycline calcium | ||
Demeclocycline calcium is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tR... | |||
TP1209 | BNP (1-32), rat TFA (133448-20-1 free base) | Brain Natriuretic Peptide (BNP) (1-32), rat TFA,BNP (1-32), rat TFA | |
Acts as a cardiac hormone with a variety of biological actions including natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. It is thought to play a key role in cardiovascular homeos... | |||
T75894 | Sauvagine TFA | ||
Sauvagine TFA, a mammalian CRF agonist derived from a 40-amino-acid neuropeptide found in frog skin, effectively releases ACTH from rat pituitary cells. It exhibits pharmacological effects on diuresis, the cardiovascular... | |||
T70097 | Acefylline piperazine | ||
Acefylline piperazine is a stimulant drug of the xanthine chemical class. It acts as an adenosine receptor antagonist. Acephylline piperazine is a theophylline derivative with a direct bronchodilator action. It has the a... |