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Results for "
dhodh-in-15
" in TargetMol Product Catalog- Inhibitors & Agonists2
DHODH-IN-15 
T110241364791-88-7In house
DHODH-IN-15 is the hydroxyfuran analogue of A771726. DHODH-IN-15 is a dihydroorotate dehydrogenase (DHODH) inhibitor with an IC50 of 11 μM for rat liver DHODH. DHODH-IN-15 can be used for rheumatoid arthritis.
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hDHODH-IN-15
T88973
hDHODH-IN-15 (Compound H19) acts as an inhibitor of human dihydroorotate dehydrogenase (hDHODH), demonstrating an IC50 of 0.21 µM. It exhibits cytotoxic effects in cancer cells such as NCI-H226, HCT-116, and MDA-MB-231, with IC50 values ranging from 0.95 to 2.81 µM. Furthermore, hDHODH-IN-15 induces ferroptosis in HCT-116 cells and shows antitumor activity.
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