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Results for "

d18:0/24:0

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    172
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    2
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    TargetMol | Activity
C24 dihydro Ceramide (d18:0/24:0)
T358106063-36-1
C24 dihydro Ceramide is a sphingolipid that has been found in the stratum corneum of human skin.[1] It is found in higher concentrations in female sebum compared to male sebum.[2] C24 dihydro Ceramide levels positively correlate with cytotoxicity in CCRF-CEM, MOLT-4, COG-LL-317h, and COG-LL-332h T cell acute lymphoblastic leukemia (ALL) cell lines.[4] Levels of C24 dihydro ceramide are increased by 149.49-fold in dihydroceramide desaturase 1 (DEGS1) knockdown UM-SCC-22A human head and neck squamous carcinoma cells in vitro.[4] C24 dihydro Ceramide levels are also increased in INS-1 β-cells incubated with glucose and palmitate.[5]
  • $598
7-10 days
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C24 (2'(R)-hydroxy) dihydro Ceramide (d18:0/24:0)
T85065164989-36-0
  • Inquiry Price
8-10 weeks
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EAD1 TFA(1644388-26-0 Free base)
T35329L2320427-95-8In house
EAD1 HCL is a potent autophagy inhibitor with antiproliferative activity in lung and pancreatic cancer cells. EAD1 HCL also induces apoptosis
  • $58
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2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid
T8833327033-56-7
2-chloro-5-(16,18-dioxo-17-azapentacyclo[6.6.5.0~2,7~.0~9,14~.0~15,19~]nonadeca-2,4,6,9,11,13-hexaen-17-yl)benzoic acid can be used to synthesize a variety of organic compounds.
  • $30
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CEF6 acetate(913545-15-0 free base)
TP1822L
CEF6 acetate is a HLA-B7 restricted influenza virus nucleoprotein epitope, belongs to the CEF control peptides. The CEF control peptides are 8-12 amino acids in length, with sequences derived from the human cytomegalovirus, Epstein-Barr virus and influenz
  • $56
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CL2A-SN-38 DCA 1279680-68-0(free base)
T17731L
CL2A-SN-38 is a drug-linker conjugate composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC).. CL2A-SN-38 is composed of a potent a DNA Topoisomerase I inhibitor SN-38 and a linker CL2A to make antibody drug conjugate (ADC). CL2A-SN-38 provides significant and specific antitumor effects against a range of human solid tumor types. CL2A is a noncleavable complicated PEG8- and triazole-containing PABC-peptide-mc linker. CL2A is cleavable through pH sensitivity, giving rise to bystander effect, and binds the antibody at a cysteine residue via a disulfide bond. .
  • $133
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Eledoisin trifluoroacetate (69-25-0 free base)
T883210129-92-7
Eledoisin trifluoroacetate (69-25-0 free base) is a peptide extracted from the posterior salivary glands of certain small octopi (Eledone spp., Mollusca), or obtained by synthesis. Its actions resemble those of SUBSTANCE P; it is a potent vasodilator and increases capillary permeability.
  • $133
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G3-C12 acetate(848301-94-0 free base)
T11346L
G3-C12 acetate shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
  • $48
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beta-Neoendorphin acetate(77739-21-0 free base)
TP2322L78658-39-6
beta-Neoendorphin acetate is an agonist of κ-opioid receptor
  • $133
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Melittin TFA(20449-79-0(free base))
TP1299L
Melittin TFA is a small protein containing 26 amino acid residues, is the principal toxic component of bee venom. Melittin is a PLA2 activator, stimulates the activity of the low molecular weight PLA2, while it does not the increase activity of the high m
  • $119
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Gly-Arg-Gly-Asp-Ser acetate(96426-21-0 free base)
TP1459L
Gly-Arg-Gly-Asp-Ser (GRGDS) acetate is a cell binding protein domain derived from the cell-binding region of fibronectin.
  • $35
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Urechistachykinin I acetate(149097-03-0 free base)
TP1019L
Urechistachykinin I acetate(149097-03-0 free base) (Uru-TK I acetate) is an invertebrate kalinin-related peptide (TRPs) isolated from thylakoid nematodes.
  • $43
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SIYRY acetate(178561-37-0 free base)
TP1548L
SIYRY acetate(178561-37-0 free base) is a Kb-restricted epitope peptide.
  • $133
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BPR1J-097 hydrochloride (1327167-19-0(free base))
T4261
BPR1J-097, a new-type small molecule FLT-3 inhibitor(IC50=11±7 nM), is with great anti-tumor activities in vivo.
  • $43
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CJC-1295 acetate(863288-34-0 free base)
TP2328L
CJC-1295 acetate(863288-34-0 free base) (DAC:GRF acetate) is a synthetic analogue of growth hormone-releasing hormone (GHRH) (also known as growth hormone-releasing factor (GRF)) and a growth hormone secretagogue (GHS)
  • $133
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RFRP3(human) acetate(311309-27-0 free base)
TP1936L1
RFRP-3(human) acetate, a human GnIH peptide homolog, is a potent inhibitor of gonadotropin secretion by inhibiting Ca2+ mobilization. RFRP-3(human) acetate is a NPFF1 receptor agonist, it inhibits forskolin-induced production of cAMP with an IC50 of 0.7 n
  • $133
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Amylin, amide, rat acetate(124447-81-0,free base)
TP1232L
Amylin, amide, rat acetate is a potent and high affinity ligand of AMY1 and AMY3 receptors and variably of AMY2 receptors.
  • $296
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Disomotide TFA 181477-43-0(free base)
T7712L
Disomotide TFA is an oligopeptide for the treatment of melanoma.
  • $50
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PQ401 hydrochloride (196868-63-0(free base))
T4324
PQ401 inhibits autophosphorylation of IGF-1R domain with IC50 of <1 μM.
  • $30
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Urotensin I acetate (83930-33-0 Free base)
TP1199L
Urotensin I acetate, a CRF-like neuropeptide, acts as an agonist of CRF receptor with pEC50s of 11.46, 9.36 and 9.85 for human CRF1, human CRF2 and rat CRF2α receptors in CHO cells, and Kis of 0.4, 1.8, and 5.7 nM for hCRF1, rCRF2α and mCRF2β receptors, respectively[1][2].
  • $250
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Mazdutide acetate(2259884-03-0 free base)
T78097L
Mazdutide acetate is a potent co-agonist of glucagon-like peptide (GLP-1R) and glucagon receptor (GCGR), a gastrin-regulating hormone analog.Mazdutide acetate stimulates insulin secretion from mouse pancreatic islets, and can be used in studies of obesity and type 2 diabetes (T2D).
  • $89
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CDK2 acetate(255064-79-0 free base)
TP1875L
CDK2 acetate is a member of the eukaryotic S T protein kinase family and its function is to catalyze the phosphoryl transfer of ATP γ-phosphate to serine or threonine hydroxyl (denoted as S0 T0) in a protein substrate.
  • $62
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MS31 trihydrochloride (2366264-12-0 free base)
T12111L
MS31 trihydrochloride (2366264-12-0 free base) is a potent, highly affinity and selective fragment-like methyllysine reader protein spindlin 1 (SPIN1) inhibitor.
  • $205
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WKYMVM 2TFA(187986-17-0(free base))
T7484L
WKYMVM 2TFA is a N-formyl peptide receptor (FPR1) agonist.
  • $89
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LGnRH-III, lamprey acetate(147859-97-0 free base)
TP1700L
LGnRH-III, lamprey acetate is an evolutionarily conserved member of the GnRH family, can stimulate the secretion of gonadotropins, it stimulates the secretion of both luteinizing and follicle-stimulating hormones.
  • $133
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BPC 157 acetate(137525-51-0 free base)
T20561L
BPC 157 acetate(137525-51-0 free base) is a 15-amino acid fragment of a gastric peptide (BPC) which has hepatoprotective effects.
  • $162
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AMPK activator 2 hydrochloride( 2410961-69-0 Free base)
T60675L
AMPK activator 2 hydrochloride is a fluoroguanidine-containing derivative that up-regulates the AMPK signaling pathway and down-regulates mTOR/4EBP1/p70S6K.AMPK activator 2 hydrochloride inhibits the proliferation and migration of human cancer cell lines (UMUC3, T24, A549).
  • $80
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SNAP8 Acetate(868844-74-0,free base)
T6990L
Diminishing the appearance of wrinkles.
  • $32
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Autocamtide-2-related inhibitory peptide, myristoylated acetate(201422-04-0 free base)
TP1921L1
Autocamtide-2-related inhibitory peptide, myristoylated acetate is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide.
  • $80
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Tripeptide-1 Acetate(72957-37-0,free)
TP2314
Tripeptide-1 Acetate is a biologically active peptide
  • $50
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difelikefalin acetate(1024828-77-0 Free base)
TP2485
is a ketone and a building block.
  • $167
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NTRC 0066-0
T282161817791-73-3In house
NTRC 0066-0 is an orally available, selective and potent inhibitor of threonine tyrosine kinase (TTK) that inhibits phosphorylation of TTK substrates and induces chromosome missegregation in cell lines and mice for cancer research.
  • $199
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Compound 1769-24-0
TPL01861769-24-0
Compound 1769-24-0 is a natural product for research related to life sciences. The catalog number is TPL0186 and the CAS number is 1769-24-0.
  • $29
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Semax acetate(80714-61-0 free base)
T21268L2828433-33-4
Semax acetate is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties.
  • $41
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Ginkgolic Acid (C13:0)
T6S212220261-38-5
Ginkgolic Acid (C13:0) (6-Tridecylsalicylic acid): 0exhibits the highest α-glucosidase inhibitory activity.
  • $35
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Tetracosanoyl-sulfatide
T38283151122-71-3
Tetracosanoyl-sulfatide is an endogenous sulfated glycolipid, which are also known as sulfatides . Tetracosanoyl-sulfatide is the major sulfatide in mature myelin in the central and peripheral nervous systems. Levels of Tetracosanoyl-sulfatide are elevated in plasma derived from patients with metachromatic leukodystrophy, a disorder characterized by arylsulfatase A deficiency, leading to sulfatide accumulation. Unlike C24:1 3'-sulfo galactosylceramide, it does not induce an immune response in mouse splenocytes in vitro.
  • $1,850
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C12 Galactosylceramide (d18:1/12:0)
T3685841613-14-3
C12 Galactosylceramide is a bioactive sphingolipid. It inhibits IL-4 production by 53.84% in EL4 T cells when used at a concentration of 10 μM. C12 Galactosylceramide reduces the growth of human papillomavirus type 16-associated tumors in mice and reduces tumor recurrence following surgical removal or chemotherapy. It also reduces natural killer T cell activity, delays the onset of proteinuria, and improves survival in a mouse model of systemic lupus.
  • $589
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Org OD 02-0
T8159813258-85-0
10-Ethenyl-19-norprogesterone (Org OD 02-0) is a selective agonist for the membrane progesterone receptor α (mPRα) with an IC50 of 33.9 nM, known to activate MAPK activity, and inhibit prolactin (PRL) secretion in the pituitary [1] [2].
  • Inquiry Price
8-10 weeks
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QTY
Lysophosphatidylcholine C19:0
T81895108273-88-7
Lysophosphatidylcholine C19:0 (1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine), an acyl chain lipid, enhances IL-1beta secretion [1].
  • Inquiry Price
8-10 weeks
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C32 Ceramide (d18:1/32:0)
T8527534227-73-1
  • Inquiry Price
8-10 weeks
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C17 dihydro Ceramide (d18:0/17:0)
T852791388156-40-8
  • Inquiry Price
8-10 weeks
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C17 Ceramide (d18:1/17:0)
T3743767492-16-4
C17 Ceramide is a synthetic ceramide that contains a non-natural C17:0 fatty acid acylated to sphingosine. It has been used as a marker of arylsulfatase A and sphingolipid activator B activity in patients undergoing enzyme replacement therapy for the genetic disease metachromatic leukodystrophy.
  • $98
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C22 Glucosylceramide (d18:1/22:0)
T38282119242-44-3
C22 Glucosylceramide (d18:1/22:0) is an endogenous glucosylceramide. Glucosylceramides are major constituents of skin lipid membranes where they play a role in maintaining the water permeability barrier. They are precursors in the synthesis of lactosylceramide , as well as oligoglycolipids and gangliosides. Phospholipase A2 (PLA2) type XIIA knockdown increases C22 glucosylceramide (d18:1/22:0) expression in rat brain. It is also increased in the brain, but not the liver or spinal cord, of mice fed a methionine-restricted diet. In human athletes, plasma levels of C22 glucosylceramide (d18:1/22:0) increase during exercise and return to basal levels during recovery. This product contains C22 glucosylceramide (d18:1/22:0) isolated from bovine buttermilk.
  • $1,998
35 days
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L 44-0
T3244195240-93-0
L 44-0 is a nicotinic acid derivative.
  • $1,520
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C8 Galactosylceramide (d18:1/8:0)
T3632341613-16-5
C8 Galactosylceramide is a synthetic C8 short-chain derivative of known membrane microdomain-forming sphingolipids. It increases the amount delivered and toxicity of doxorubicin in cancerous but not non-cancerous cells when incorporated into the nanoliposomal membrane of nanoliposomal-doxorubicin. C8 Galactosylceramide induces proliferation and cytokine production by splenocytes in vitro at concentrations ranging from 100-1,000 ng/ml but has no effect on natural killer T cell production in vivo. It also activates NF-κB production in C6 glioma cells when used at a concentration of 10 μM.
  • $777
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PE(10:0/10:0)
T66959
PE(10:0/10:0) is a useful organic compound for research related to life sciences and the catalog number is T66959.
    7-10 days
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    16:0 TAP
    T74290139984-36-4
    16:0 TAP, a lipid compound, is utilized in the preparation of giant unilamellar vesicles for agent delivery [1].
    • $125
    35 days
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    C19 Ceramide (d18:1/19:0)
    T3587367492-17-5
    C19 Ceramide is a naturally occurring ceramide that has been found in J. juncea extracts as well as rat brain and mouse heart.[1],[2],[3] It is elevated in adult and decreased in juvenile whole rat brain extracts by 114 and 37%, respectively, following chronic ethanol exposure.[2] C19 Ceramide is also increased in mouse hearts following administration of angiotensin II.[3]
    • $51
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