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cytosolic thioredoxin reductase 1 (txnrd1)

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
LCS3
T60446109844-92-0
LCS3 is a reversible and non-competitive synergistic inhibitor of glutathione disulfide reductase (GSR) and thioredoxin reductase 1 (TXNRD1) with IC50s of 3.3 μM and 3.8 μM, respectively. LCS3 has antitumour activity, induces apoptosis and can be used in the study of lung adenocarcinoma (LUAD).
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6-8 weeks
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TRi-1
T5481246020-68-8
TRi-1 is irreversible inhibitor of cytosolic thioredoxin reductase 1 (TXNRD1), with an IC50 of 12 nM. TRi-1 has little mitochondrial toxicity for anticancer therapy
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