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Results for "
cyclosporin d
" in TargetMol Product Catalog.- Inhibitors & Agonists3
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- Natural Products1
Cyclosporin D
TP166563775-96-2
Cyclosporin D is a metabolite of Cyclosporin A, retaining the cyclic peptide structure of cyclosporins but exhibiting relatively weaker immunosuppressive activity. It is sometimes used as an internal standard or reference compound in analytical studies. Cyclosporin A inhibits Calcineurin activity, thereby blocking NFAT-mediated transcriptional activation and suppressing T cell activation.
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2-[O-(2-Azidoethyl)-D-serine]-cyclosporin A
TP4215164028-89-1
2-[O-(2-Azidoethyl)-D-serine]-cyclosporin A (Compound 33) is a derivative of Cyclosporine. This compound exhibits an IC50 of 0.11 μg/mL in mixed lymphocyte reaction assays.
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H-D-MeAla-EtVal-Val-MeLeu-AIa-D-AIa-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe
T822221038781-13-3
H-D-MeAla-EtVal-Val-MeLeu-Ala-D-Ala-MeLeu-MeLeu-MeVal-MeBmt(OAc)-Abu-O-CH2-CH2-NHMe is a derivative of cyclosporin A, lacking immunosuppressive properties, with potential applications in congenital muscular dystrophy research [1].
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