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cot inhibitor-2

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Cot inhibitor-2
T10866915363-56-3In house
Cot inhibitor-2 is a cot (Tpl2 MAP3K8) inhibitor (IC50: 1.6 nM) with potency, selectivity and oral activity. cot inhibitor-2 inhibits LPS-stimulated TNF-α production in human whole blood with an IC50 of 0.3 μM.
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4-6 weeks
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Cot inhibitor-1 hydrochloride
Cot inhibitor-1 hydrochloride(915365-57-0 Free base)
T10865L In house
Cot inhibitor-1 hydrochloride is an inhibitor of tumor progression loci-2 kinase (IC50 = 28 nM) and inhibits the production of TNF-α in human whole blood (IC50 = 5.7 nM).
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