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chs-828 nicotinic acid, chs 828

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
ArgTX-93 TFA
T713591161025-20-2
ArgTX-93 is a highly potent and subfamily selective antagonist of the NMDARs and AMPARs.
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8-10 weeks
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CHS-828 nicotinate
T713611160589-73-0
CHS-828 nicotinate is a CHS-828 salt with Nicotinic acid.. CHS-828 also known as GMX-1778, is a potent and selective NAMPT inhibitor. CHS-828 inhibits cellular synthesis of NAD. CHS 828 kill tumour cells by inhibiting the nuclear factor-kappaB translocation but unlikely through down-regulation of proteasome. CHS 828 has shown promising anticancer activity in experimental tumor models and primary cultures of cancer cells from patients. CHS 828 showed a synergistic effect with melphalan in 67%, doxorubicin in 47%, etoposide in 38% and Ara-C in 14% of AML samples.
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6-8 weeks
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