chlorazanil hydrochloride

Chlorazanil hydrochloride is the hydrochloride form of Chlorazanil.Chlorazanil, a triazine derivative, is an orally effective diuretic that blocks the absorption of sodium and chloride in the distal tubule.

Chlorazanil is a triazine-derived compound that functions as a novel, orally active, and non-toxic diuretic. Chlorazanil exerts its pharmacological effect by selectively blocking sodium and chloride ion reabsorption in the distal renal tubule, promoting diuresis and modulating electrolyte balance without inducing significant systemic toxicity, in addition, chlorazanil increases renal prostaglandin activity by increased prostaglandin synthesis,marking it as a valuable agent in renal physiology research and diuretic drug development.