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(2)
By Target- JNK
- EGFR(1)
- ERK(1)
- p38 MAPK(1)
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Results for "
cc 930
" in TargetMol Product Catalog- Inhibitors & Agonists2
Tanzisertib
CC-930
T14895899805-25-5
Tanzisertib (CC-930) (CC-930) is a potent inhibitor of JNK1 2 3 with IC50s of 61 7 6 nM, respectively, with potential antifibrotic activity.
- $35
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QTY
(3S)-Tanzisertib hydrochloride
(3S)-CC-930 hydrochloride
T2073422517855-91-1
(3S)-Tanzisertib (hydrochloride) ((3S)-CC-930 (hydrochloride)) is an orally active JNK inhibitor, exhibiting IC50 values of 61 nM for JNK1, 7 nM for JNK2, and 6 nM for JNK3. It selectively inhibits ERK1, p38α, and EGFR, with IC50 values of 0.48 μM, 3.4 μM, and 0.38 μM, respectively. In an acute rat PK-PD model, (3S)-Tanzisertib (hydrochloride) suppresses LPS-induced TNFα production and is utilized in research on idiopathic pulmonary fibrosis (IPF).
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