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By Target- Apoptosis
- Caspase(1)
- Wnt/beta-catenin(1)
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Results for "
casp 7
" in TargetMol Product Catalog- Inhibitors & Agonists1
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XIAP-CASP7 PPI-IN-1
T211590
XIAP-CASP7 PPI-IN-1 is a reversible inhibitor of the XIAP:CASP7 interaction, effectively disrupting the connection between XIAP and CASP7. It selectively induces apoptosis in MCF-7 and caspase-3 low-expression (CASP3/DR) triple-negative breast cancer cells. The compound overcomes chemoresistance by down-regulating β-catenin and associated ABC transporters in paclitaxel-resistant MCF-7 cells. XIAP-CASP7 PPI-IN-1 is useful for breast cancer research.
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