carbovir

Carbovir, also known as (-)-Carbovir, is a nucleoside nucleotide reverse transcriptase inhibitor (NRTI) caused mitochondrial toxicity in human hepatoma carcinoma cell.

(+)-Carbovir is a nucleoside analog with increased chemical stability and increased metabolic stability.

CNV-2197944 is a novel, small molecule, state-dependent calcium channel blocker, designed to selectively inhibit highly active Cav2.2 channels.

(+)-Carbovir triphosphate, an active metabolite of Abacavir, was utilized to study the molecular mechanism of inhibition and drug resistance in HIV-1 reverse transcriptase.

Carbovir triphosphate (CBV-TP), a phosphorylated metabolite, serves as a research tool for studying human immunodeficiency virus (HIV) [1].

rel-Carbovir monophosphate is the enantiomer of the cyclopropyl analogue of 2',3'-dideoxy-2',3'-didehydroguanine and Carbovir (CBV). As an HIV replication inhibitor, Carbovir specifically blocks the incorporation of nucleic acid precursors into DNA.

ent-Abacavir is an enatiomer of Abacavir. Abacavir is a carbocyclic 2'-deoxyguanosine nucleoside reverse transcriptase inhibitor and an anti-HIV drug used to treat HIV infection. Intracellular enzymes convert Abacavir to its active form, carbovir-triphosphate (CBV-TP), which then selectively inhibits HIV reverse transcriptase by incorporating into viral DNA. Abacavir is metabolized in the liver by uridine diphosphate glucuronyltransferase and alcohol dehydrogenase resulting in inactive glucuronide and carboxylate metabolites, respectively.