c. trachomatis

Rosoxacin (Acrosoxacin) shows antibacterial activities against a broad spectrum of Gram-negative bacteria including Neisseria gonorrhoeae (MIC90 = 0.03mg ml).

3-hydroxy Docosanoic acid is a hydroxylated form of the 22-carbon saturated docosanoic acid . It is found in lipopolysaccharides from C. trachomatis and C. psittaci and in S. synnaedendra. 3-hydroxy Docosanoic acid, in the form of an acyl-CoA metabolite, is an intermediate in fatty acid chain elongation from arachidic acid to docosanoic acid (C22:0).

Saccharocarcin A is an antibiotic originally isolated from [S. aerocolonigenes subsp. antibiotica]. It demonstrates activity against [M. luteus], [S. aureus], [E. coli], [P. aeruginosa], and [C. albicans] in a disc assay and inhibits [C. trachomatis] infection by 88% without inducing cytotoxicity in McCoy cells at a concentration of 0.5 μg ml.

KSK213 is a potent inhibitor of Chlamydia trachomatis Infectivity (EC50 = 60 nM). KSK213 potently inhibited multiple serovars of C. trachomatis while not affecting the growth of key species from the commensal flora or host cell viability at 25 μM.