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  • c-Met/HGFR
    (3)
  • ALK
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c-met (y1235d)

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  • Inhibitors & Agonists
    3
    TargetMol | Inhibitors_Agonists
MK-2461
MK2461
T6094917879-39-1In house
MK-2461 is a novel inhibitor that targets multiple proteins and competitively binds to ATP sites, specifically inhibiting the activated c-Met protein with an average inhibitory concentration (IC50) of 2.5 nM.
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Crizotinib
PF-02341066
T1661877399-52-5
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinase inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptors.
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TargetMol | Citations Cited
c-Met-IN-22
T208756
c-Met-IN-22 (compound 51am) is an orally active c-Met inhibitor with an IC50 value of 2.54 nM. It exhibits both antiproliferative and antitumor activities and can induce apoptosis.
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