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(2)
By Target- c-Fms
- c-Kit(2)
- Autophagy(1)
- FGFR(1)
- JNK(1)
- PDGFR(1)
- VEGFR(1)
- Others(1)
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Results for "
c fms in 10
" in TargetMol Product Catalog- Inhibitors & Agonists4
c-Fms-IN-10
T106441527517-50-5
c-Fms-IN-10, a derivative of thieno [3,2-d] pyrimidine, is a kinase inhibitor of FMS (Colony-stimulating factor-1 receptor, CSF-1R; IC50: 2 nM) with anti-tumor activity.
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JNK-IN-8
Cited
JNK Inhibitor XVI
T26681410880-22-6
JNK-IN-8 (JNK Inhibitor XVI) is an irreversible JNK1 2 4 inhibitor (IC50: 4.7 18.7 1 nM) with over 10-fold selectivity compared to MNK2 and Fms, and no inhibition of Met, c-Kit, or PDGFRβ in the A375 cell line.
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CitedGW786034B
Votrient HCl, Pazopanib HCl, GW786034 HCl
T6930635702-64-6
Pazopanib Hydrochloride (Votrient HCl) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms with IC50 of 10 nM, 30 nM, 47 nM, 84 nM, 74 nM, 140 nM and 146 nM in cell-free assays, respectively.
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c-Fms-IN-6
T106451628574-81-1
c-Fms-IN-6 is a potent inhibitor of c-FMS (IC50 ≤10 nM for unphosphorylated c-FMS) and weakly inhibits unphosphorylated c-KIT and PDGFR (IC50: >1 μM).
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