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beta-muricholic acid

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Tauro-β-muricholic acid sodium
T-βMCA sodium
T13093145022-92-0
Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM).
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β-Muricholic Acid
β-MCA,5β-Cholanic Acid-3α,6β,7β-triol,β-Muricholic Acid
T354002393-59-1
β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.[4]
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35 days
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