batabulin sodium

Batabulin sodium (T138067 sodium) is an antitumor agent that covalently and selectively modifies β-tubulin isotypes, disrupting microtubule polymerization, affecting cell morphology, leading to cell-cycle arrest, and ultimately inducing apoptotic cell death [1].

Batabulin (T138067) is an antitumor compound that binds covalently and selectively to a subset of the β-tubulin isotypes, disrupting microtubule polymerization. This disruption affects cell morphology, induces cell-cycle arrest, and ultimately leads to apoptotic cell death.