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By Target- BACE
- Beta Amyloid(1)
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Results for "
bace1in5
" in TargetMol Product Catalog- Inhibitors & Agonists1
BACE1-IN-5
T104532581114-83-0
BACE1-IN-5 (Compound 15), a potent β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, demonstrates significant efficacy with an IC50 of 9.1 nM for BACE1 inhibition and an impressive IC50 of 0.82 nM against cellular amyloid-β (Aβ) production. Additionally, it is engineered to enhance hERG inhibition and P-gp efflux, indicating its optimized medicinal chemistry profile [1].
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