b32b3

B32B3 is a VprBP inhibitor with anti-tumor activity. By blocking H2AT120p and reactivating a transcription program similar to normal cells, it inhibits the growth of colon tumors.

Microtubule destabilizing agent-3 is an analogue of B32B3 and functions as a microtubule destabilizer. By destabilizing microtubules and promoting mitotic arrest, it exerts its anti-myeloma phenotype, ultimately leading to cell death. Microtubule destabilizing agent-3 induces G2/M phase arrest and caspase-dependent apoptosis (apoptosis) and can be utilized in research on multiple myeloma.

Microtubule destabilizing agent-3, negative control, is an analog of B32B3 and serves as the negative control for Microtubule destabilizing agent-3. This agent functions as a microtubule destabilizer by disrupting microtubule stability, which promotes mitotic arrest and exhibits an anti-myeloma phenotype, ultimately leading to cell death. It can also induce G2/M phase arrest and caspase-dependent apoptosis.