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az12601011

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
AZ12601011
AZ 12601011, AZ-12601011
T104262748337-86-0
AZ12601011 is an orally active, selective and potent TGFBR1 kinase inhibitor.AZ12601011 inhibits the release of inflammatory factors, interleukin (IL)-1β, IL-6 and tumor necrosis factor-α, and inhibits the growth of breast tumors.AZ12601011 directly binds to TGF-βR1 and blocks downstream Smad3 activation, which can be used to prevent renal fibrosis.
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10-14 weeks
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