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aspergillosis

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Isavuconazonium sulfate
T3934946075-13-4
Isavuconazonium sulfate is hydrolyzed by plasma esterases to yield the active moiety isavuconazole. Isavuconazole binds to and inhibits the fungal cytochrome P450 family enzyme lanosterol 14-alpha-demethylase (CYP51), which catalyzes the demethylation of
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Micafungin metabolite M1
TP3139539823-80-8
Micafungin metabolite M1 is one of the major metabolites of the antifungal drug micafungin, generated via arylsulfatase-mediated metabolism. Micafungin metabolite M1 retains limited antifungal activity and exhibits in vitro inhibitory effects against fungi such as Candida and Aspergillus. It is commonly used in studies of micafungin metabolism and antifungal mechanisms.
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