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Results for "
art558
" in TargetMol Product Catalog- Inhibitors & Agonists3
ART899
T2013652607139-85-3
ART899, a derivative of ART558, is a potent and specific conformational inhibitor of DNA polymerase θ (Polθ). It specifically inhibits the MMEJ activity of Polθ with an IC50 of 180 nM. Additionally, ART899 selectively enhances the radiosensitivity of tumor cells and possesses a strong independent antitumor effect on cancer cells.
- $2,570
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