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Results for "
apto-253 isomer
" in TargetMol Product Catalog- Inhibitors & Agonists2
APTO-253 isomer
T707061422826-80-9
APTO-253 isomer is an isomer of APTO-253 with the Fluoro-atom in 6-position. APTO-253 also known as LOR-253, LT-253, is a small molecule inhibitor of human metal-regulatory transcription factor 1 (MTF-1) with potential antitumor activity. MTF-1 inhibitor LOR-253 inhibits MTF-1 activity and thereby induces the expression of MTF-1 dependent tumor suppressor factor Kruppel like factor 4 (KLF4). This subsequently leads to the downregulation of cyclin D1, blocking cell cycle progression and proliferation. This agent also causes decreased expression of genes involved in tumor hypoxia and angiogenesis.
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Flufenacet
T71948142459-58-3
Flufenacet is a herbicide, inhibiting very-long-chain fatty acid elongase (VLCFAE) synthesis.
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