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Results for "
aps-2-79
" in TargetMol Product Catalog- Inhibitors & Agonists3
aps-2-79
T700042002381-25-9
APS-2-79, a KSR-dependent MEK antagonist, disrupts ATP (biotin) binding within the KSR2-MEK1 complex, achieving an inhibitory concentration (IC50) of 120 nM. This action stabilizes the KSR inactive state and antagonizes oncogenic Ras-MAPK signaling.
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APS-2-79 hydrochloride
APS-2-79 HCl
T67602002381-31-7
APS-2-79 hydrochloride (APS-2-79 HCl) is a MAPK antagonist that modulating KSR-dependent MAPK signalling by antagonizing RAF heterodimerization as well as the conformational changes required for phosphorylation and activation of KSR-bound MEK.
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