anticonvulsive

(S)-Mephenytoin ((+)-Mephenytoin) is an anticonvulsant that serves as a substrate of the cytochrome P450 (CYP) isoform CYP2C19 and is used to analyze cytochrome P450 metabolism.

Vanillyl Alcohol (3-Methoxy-4-hydroxybenzyl alcohol) possesses anti-angiogenic, anticonvulsive, anti-inflammatory, anti-oxidant, neuroprotective, and anti-nociceptive activities. Vanillyl alcohol can effectively inhibit the cytotoxicity and improved cell viability in 1-methyl-4-phenylpyridinium (MPP+)-induced MN9D dopaminergic cells, it also can attenuate the elevation of reactive oxygen species (ROS) levels, decrease in the Bax Bcl-2 ratio and poly (ADP-ribose) polymerase proteolysis.

1. p-Hydroxybenzaldehyde (p-Oxybenzaldehyde) shows an inhibitory effect on the GABA transaminase to contribute to an antiepileptic and anticonvulsive activity, and its inhibitory activity was higher than that of valproic acid, a known anticonvulsant.

(RS)-PPG is a potent and selective group III mGluRs agonist (EC50s of 5.2 μM, 4.7 μM, 185 μM, and 0.2 μM for hmGluR4a, hmGluR6, hmGluR7b, and hmGluR8a, respectively), with neuroprotective and anticonvulsive activity.

LY 81067 is a new anticonvulsive compound that effectively protects against pentylenetetrazole- and picrotoxin-induced convulsions in mice. It exerts its anticonvulsant effects by binding to or near picrotoxin binding sites.

Withaphysalin R (compound 5), a withanolide derived from the Solanaceae family, possesses an ergosterol-based steroid ester structure. This compound exhibits notable activities such as cytotoxic, immunosuppressive, antitumor, anti-inflammatory, anticonvulsive, and antioxidant effects [1].

Lisuride maleate is a non-selective dopamine agonist and G-protein-biased 5-HT2A receptor agonist capable of blocking prolactin release. Lisuride maleate may be employed in studies of Parkinson's disease, depression, and hyperprolactinemia disorders.

Cortistatin 14, human, rat acetate is a neuropeptide having structural similarity to somatostatin-14 and shows anticonvulsive, neuroprotective effects and remarkable anti-inflammatory properties. Cortistatin 14, human, rat acetate binds and exerts its fun

Cortistatin-14 acetate, a neuropeptide have structural similarity to somatostatin-14, binds and exerts its function via the somatostatin receptors (sst1-sst5). Cortistatin-14 acetate shows anticonvulsive, neuroprotective effect and remarkable anti-inflammatory properties