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By Target- EGFR
- c-Met/HGFR(2)
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- Bradykinin Receptor
- cAMP
- Cannabinoid Receptor
- CaSR
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- cholecystokinin
- CRFR
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- GTPase
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- Functional assay(3)
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Search Result
Results for "
amivantamab
" in TargetMol Product Catalog- Inhibitors & Agonists1
- Inhibitory Antibodies3
Amivantamab
JNJ-61186372, JNJ61186372
T9901A-15512171511-58-1
Amivantamab (JNJ-61186372) is a humanized antibody that recognizes epidermal growth factor receptor (EGFR) and MET proto-oncogene (MET), with anticancer and anti-tumor activities, preventing ligand binding to EGFR and MET and receptor dimerization that inhibits downstream signal transduction. Amivantamab can induce Fc-dependent endocytosis of macrophages and antibody-dependent cytotoxicity of natural killer cells, and can be used to study metastatic non-small cell lung cancer.
Inquiry
Amivantamab (FUT8-KO)
T9901A-232
Amivantamab (FUT8-KO) is a humanized dual-specificity antibody targeting EGFR-MET, with FUT8 knocked out, exhibiting immunotherapeutic anticancer activity. This compound inhibits ligand binding, enhances the internalization and degradation of receptor-antibody complexes, and stimulates macrophage-mediated phagocytosis and natural killer cell cytotoxicity, both of which are Fc-dependent.
- Inquiry Price
Size
QTY
Amivantamab (Anti-c-Met)
JNJ61186372 (Anti-c-Met), JNJ-61186372 (Anti-c-Met), JNJ 61186372 (Anti-c-Met)
T77110
Amivantamab (Anti-c-Met) is a human antibody that recognizes the MET proto-oncogene (MET) and can be used in cancer-related research.
- $289
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