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am 679

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
AM679
T142051206880-66-1
AM679 is a potent and selective FLAP inhibitor with IC50s of 2.2 nM/0.6 nM/154 nM for FLAP binding/hLA/hWB respectively. IC50 value: 2.2 nM/0.6 nM/154 nM(FLAP binding/hLA/hWB) [1] AM679 showed an improved CYP inhibition profile (IC50 3A4 = 16.7 lM, 2C9 =
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10-14 weeks
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