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acyvadcho

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Ac-YVAD-CHO
L709049, L-709049, L 709049
T19883143313-51-3
Ac-YVAD-CHO (L 709049) is a selective and potent tetrapeptide interleukin 1β-converting enzyme (ICE) and caspase-1 (ICE)-like protease inhibitor with anti-inflammatory activity, inhibits cancer cell growth, and inhibits the production of mature IL-lβ. Ac-YVAD-CHO attenuates quinolinic acid-induced p53 increase and apoptosis in rat striatum.
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Ac-YVAD-CHO acetate
T73852
Ac-YVAD-CHO (L-709049) acetate is a potent, reversible, and specific tetrapeptide interleukin-1β converting enzyme (ICE) inhibitor, also demonstrating specificity for caspase-1. It exhibits K_i values of 3.0 nM in mice and 0.76 nM in humans, underscoring its efficacy. Additionally, Ac-YVAD-CHO acetate inhibits the production of mature IL-1β, highlighting its therapeutic potential [1] [2] [3].
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