acetoacetyl-coa

Acetoacetyl CoA serves as a precursor to HMG-CoA in the mevalonate pathway. Catalyzed by acetoacetyl-CoA thiolase, it is formed from two acetyl-CoA molecules. Acetoacetyl CoA is vital for cholesterol biosynthesis and also acts as an intermediate in both the breakdown and synthesis of fatty acids.

Acetoacetyl CoA sodium hydrate is a precursor of HMG-CoA in the mevalonate pathway. The enzyme acetoacetyl-CoA thiolase catalyzes the formation of acetoacetyl CoA sodium hydrate from two acetyl-CoA molecules. This compound is crucial for cholesterol biosynthesis and serves as an intermediate in both fatty acid catabolism and synthesis.

2-Methylacetoacetyl-COA (2-Methylacetoacetyl-coenzyme A) is a type of 3-oxoacyl Coenzyme A.

Acetoacetyl Coenzyme A sodium hydrate is a precursor of poly-β-hydroxybutyrate, which is closely related to the body's energy metabolism.

Butanoic acid is an endogenous human metabolite, an endogenous histone deacetylase (HDAC) inhibitor. The IC50 of HDAC3, HDAC4 and HDAC1 were 2.4 mM, 4.5 mM and 5.3 mM, respectively. 3-Hydroxybutyric acid has the effects of energy metabolism, neuroprotection, anti-inflammatory, and improvement of insulin resistance.

GSK2194069 is an active β-keto reductase (KR)-specific inhibitor of fatty acid synthase (FASN) with an IC50 of 7.7 nM in an assay for the detection of released CoA.GSK2194069 inhibits the proliferation of FAS in cancer cells through the action of acetoacetyl-coenzyme A and NADPH.

6-Methyluracil, also known as Pseudothymine, is a metabolite derived from Uracil. It serves as an indicator for the accumulation of acetoacetyl-CoA (AACoA). Additionally, 6-Methyluracil has been observed to possess antiradiation properties in vivo.