acarbose

Acarbose (BAY g 5421) is a hypoglycemic agent that is an inhibitor of orally active alpha-glucosidase (IC50=11 nM). Acarbose enhances the hypoglycemic effect of sulfonylureas or insulin.

Acarbose sulfate is an anti-diabetic drug and is an inhibitor of alpha-glucosidase.

Acarbose (Standard) is the standard substance of Acarbose, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Acarbose (BAY g 5421) is a hypoglycemic agent that is an inhibitor of orally active alpha-glucosidase (IC50=11 nM). Acarbose enhances the hypoglycemic effect of sulfonylureas or insulin.

Sulfaethoxypyridazine is a sulfonamide antibacterial agent that enhances the efficacy of drugs such as Acarbose when used in combination therapy and can induce cataracts in rats and dogs.

α-Glucosidase-IN-82 (compound 8l) is a potent inhibitor of α-glucosidase, with an IC50 value of 13.66 μM. Its inhibitory activity is 52 times greater than that of Acarbose.

α-Glucosidase-IN-79 (Compound 4d9) is a non-competitive α-glucosidase inhibitor with an IC50 of 2.11 μM, demonstrating greater inhibitory potency than the existing α-glucosidase inhibitors Acarbose (IC50 of 327.0 μM) and HXH8r (IC50 of 15.32 μM). It exhibits no cytotoxicity on normal human liver cells (LO2) and shows good metabolic stability in rat plasma. α-Glucosidase-IN-79 holds promise for research in type 2 diabetes.

Valienamine, an alpha-glucosidase inhibitor, is the crucial functional component of several natural glycosidase inhibitors, such as the crop protectant validamycin A and the antidiabetic agent acarbose [1].

Sulfaethoxypyridazine (Standard) is the standard substance of Sulfaethoxypyridazine, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Sulfaethoxypyridazine is a sulfonamide antibacterial agent that enhances the efficacy of drugs such as Acarbose when used in combination therapy and can induce cataracts in rats and dogs.