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Results for "
aacocf 3
" in TargetMol Product Catalog- Inhibitors & Agonists1
AACOCF3
Arachidonyltrifluoromethane, Arachidonyl trifluoromethyl ketone
T21681149301-79-1In house
AACOCF3 (Arachidonyl trifluoromethyl ketone) is a cell-permeable trifluoromethyl ketone analog of arachidonic acid and a potent, selective slow binding inhibitor of the 85-kDa cytosolic phospholipase A2 (cPLA2). By blocking the production of arachidonate and 12-hydroxyeicosatetraenoic acid in calcium ionophore-challenged platelets, AACOCF3 hinders their synthesis. Additionally, AACOCF3 inhibits glucose-induced insulin secretion from isolated rat islets, making it promising for cardiovascular disease research.
- $70
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