TN1162

Dibutyl phthalate (1,2-Benzenedicarboxylic acid) is a plasticizer, commonly used in industrial manufacturing, that causes cardiac damage by disrupting Ca(2+) transfer from the endoplasmic reticulum to the mitochondria and triggering subsequent cellular death.Dibutyl phthalate induces oxidative damage in the brain of zebrafish.

NADPH is an essential electron donor in organisms, providing reducing power for anabolic reactions and redox balance, and has potential for electrosynthesis. The cellular NADPH homeostasis is associated with tumor development. As a critical factor in the cellular antioxidant system, NADPH can mediate cell death through its impact on oxidative stress. This NADPH-based approach to modulate metabolism holds promise for research in the field of cancer treatment.

β-Nicotinamide mononucleotide, reduced form (NMNH) disodium is the reduced variant of β-Nicotinamide mononucleotide, with oral bioavailability. This compound significantly increases NAD+ and NADH levels while inhibiting glycolysis, the tricarboxylic acid cycle, and cell growth, mechanisms that are dependent on nicotinamide mononucleotide adenylyltransferase (NMNAT).