T21654

1-Oleoyl lysophosphatidic acid sodium (1-Oleoyl lysophosphatidic acid sodium salt) salt is an Endogenous agonist of LPA1 and LPA2

TCO-amine hydrochloride is a PROTAC linker in the alkyl chain category. It is utilized in the synthesis of PROTAC molecules and functions as a click chemistry reagent. With a TCO group, it can undergo the inverse electron demand Diels-Alder reaction (iEDDA) with molecules containing Tetrazine groups.

5-Br-6-F-Desamino lenalidomide is a ligand for the E3 ubiquitin ligase cereblon (CRBN), used for recruiting cereblon proteins. It can be linked to a target protein ligand through a linker to form PROTAC.

CRBN ligand-755 is an E3 ubiquitin ligase cereblon (CRBN) ligand that facilitates the recruitment of cereblon proteins. It can be linked to a target protein ligand via a linker to form a PROTAC.

6-Chlorohexanoic acid (ε-Chlorocaproic acid) is a PROTAC linker suitable for the synthesis of PROTAC molecules.

But-3-yn-1-yl methanesulfonate is a PROTAC linker used in the synthesis of PROTAC molecules.

tert-Butyl (3-(hydroxymethyl)bicyclo[1.1.1]pentan-1-yl)carbamate is a PROTAC linker used in the synthesis of PROTAC molecules.

ERα ligand3 is a PROTAC target protein ligand that specifically targets ERα. It can be utilized in the synthesis of CV2a.

PROTACCDK2/4 Degrader-1 (Compound 5) is a potent CDK2/4 PROTAC degrader with a DC50 of ≤ 10 nM for both CDK2 and CDK4. It demonstrates excellent activity in inhibiting cell proliferation in OVCAR3 and T47D cell lines. This compound is applicable for breast cancer and ovarian cancer research.

4,4'-(Hexane-1,6-diylbis(oxy))dibenzonitrile is a PROTAC linker employed in the synthesis of PROTAC molecules.

CRBN ligand-699 is a cereblon (CRBN) E3 ubiquitin ligase ligand used for recruiting cereblon proteins. It can be linked to a target protein ligand via a linker to form a PROTAC.