T21272

Isophthalamide is a bioactive chemical.

CDK2-IN-55 is a potent and highly selective cyclin-dependent kinase 2 (CDK2) inhibitor (IC50 = 15 nM). It disrupts the cell cycle machinery to specifically induce G1/S phase arrest in cancer cells, showing excellent anti-clonogenic and anti-proliferative activities in various gastrointestinal tumor models.

5CF2PB is a novel synthetic antibacterial molecule targeting multidrug-resistant bacteria. It exerts significant bactericidal effects against strains including methicillin-resistant S. aureus by specifically interfering with the cross-linking of key cell wall components, disrupting pathogen membrane stability and inhibiting target enzymes.

HD-800 is a highly bioactive and selective SIRT2 deacetylase inhibitor (IC50 = 37 nM). It exhibits excellent selectivity over SIRT1/3/5 isoforms and regulates tumor cell mitosis alongside neuroprotective effects by drastically increasing intracellular tubulin acetylation levels.

α1A/1D-Adrenoceptor antagonist-1 is a dual-targeting adrenoceptor antagonist exhibiting exceedingly high binding affinity for both alpha 1A and alpha 1D subtypes. It significantly reduces urethral resistance by specifically blocking smooth muscle contraction in the lower urinary tract and prostate, serving as an important tool for investigating benign prostatic hyperplasia (BPH) and hypertension mechanisms.

3-[2-[(2-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one is a high-purity biochemical reagent suitable for use as a biomaterial or an organic synthesis intermediate, and is widely used in research and experiments in the life sciences.

Losmapimod hydrochloride (GW856553X) is an orally active, potent, and highly selective p38 alpha/beta MAPK inhibitor (IC50 = 0.8 nM). It greatly reduces the release of pro-inflammatory cytokines, including TNF-alpha and IL-6, by blocking inflammatory signaling cascades, showing remarkable efficacy in COPD and severe cardiovascular inflammation models.

Riamilovir sodium (Triazavirin) is a novel guanine nucleoside analogue and broad-spectrum antiviral candidate. It completely blocks viral RNA synthesis and transcription by competitively inhibiting viral RNA-dependent RNA polymerase, demonstrating exceptionally potent in vitro neutralizing activity against various strains, including H5N1 avian influenza and multidrug-resistant variants.

H27485 is a high-affinity dopamine transporter (DAT) inhibitor (Ki = 6.3 nM) that modulates neural signaling by blocking dopamine reuptake; it is commonly used in pharmacological studies of the dopaminergic system and related neurological disorders.

WAY-637845 is a high-purity biochemical reagent suitable for biochemical experiments and drug synthes is research.