T1884

CX516 (Ampalex), an ampakine and nootropic, acts as an AMPA receptor positive allosteric modulator as a therapy for Alzheimer's disease, schizophrenia and mild cognitive impairment (MCI).

Thiol-PEG5-acid is a PEG-based linker for PROTACs that connects two essential ligands indispensable for the formation of PROTAC molecules, facilitating selective protein degradation using the ubiquitin-proteasome system within cells.

Thiol-PEG5-alcohol, a PEG-based linker for PROTACs, connects two essential ligands crucial for PROTAC molecule formation and facilitates selective protein degradation via the ubiquitin-proteasome system within cells.

Thiol-PEG6-acid is a PEG-based linker for PROTACs, joining two essential ligands vital for PROTAC molecule formation. This linker facilitates selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG8-alcohol is a PEG-based linker for PROTACs, joining two essential ligands crucial for forming PROTAC molecules and enabling selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thiol-PEG9-alcohol, a PEG-based linker for PROTACs, joins two essential ligands, crucial for forming PROTAC molecules, and enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG11-OH is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the selective protein degradation process through the ubiquitin-proteasome system within cells.

THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker used in synthesizing PROTAC K-Ras Degrader-1, as documented in reference [1].

THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, aids in the synthesis of PROTAC K-Ras Degrader-1[1].

Tos-PEG12-Tos is a PEG-based linker for PROTACs, facilitating the conjugation of two essential ligands [Tosyl(Tos)] critical for the formation of PROTAC molecules, and enabling selective protein degradation via the ubiquitin-proteasome system within cells.

Tos-PEG13-Boc, a PEG-based linker for PROTACs, facilitates the connection of two essential ligands necessary for PROTAC molecule formation, enabling selective protein degradation via the ubiquitin-proteasome system within cells.