T1623

Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor effective against HIV protease with the Val 82 mutation. It is less affected by serum protein binding compared to the structurally related drug ritonavir.

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker designed for synthesizing proteolysis targeting chimeras (PROTACs)[1].

N-Mal-N-bis(PEG2-NHS ester) is a polyethylene glycol (PEG)-based linker used in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-Mal-N-bis(PEG4-amine) is a PEG-based linker used in PROTAC synthesis [1].

N-Mal-N-bis(PEG4-NH-Boc) is a PEG-based PROTAC linker used in the synthesis of PROTACs[1].

N-Mal-N-bis(PEG4-NHS ester) is a polyethylene glycol (PEG)-based bifunctional linker used for synthesizing Proteolysis Targeting Chimeras (PROTACs) [1].

N-(Mal-PEG6)-N-bis(PEG3-amine) is a Polyethylene Glycol (PEG)-based proteolysis targeting chimera (PROTAC) linker used in the synthesis of PROTACs[1].

N-Me-N-bis(PEG2-propargyl) is a PEG-based linker used in the synthesis of PROTACs [1].

N-Me-N-bis-PEG4 is a PEG-based linker integral to PROTACs, facilitating the conjugation of two essential ligands that form PROTAC molecules, thereby enabling selective protein degradation through the ubiquitin-proteasome system within cells.

N-Methyl-N-(t-Boc)-PEG4-acid, a polyethylene glycol (PEG) derivative, is used as a PROTAC linker in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Lopinavir-D8 is a deuterated compound of Lopinavir. Lopinavir (T1623) has a CAS number of 192725-17-0. Lopinavir (T1623) is a peptidomimetic HIV protease inhibitor that retains activity against HIV protease with the Val 82 mutation. Lopinavir (T1623) is less affected by binding to serum proteins than the structurally-related drug ritonavir.