T12861

SB-277011 (SB-277011A) is a specific antagonist of the dopamine D3 receptor with pKi values of 8.0, 6.0, 5.0, and <5.2 for D3 receptor, D2 receptor, 5-HT1D, and 5-HT1B respectively.

(2E)-6-{3a,6,6,9a,11a-pentamethyl-4,7-dioxo-1H,2H,3H,3aH,4H,5H,5aH,6H,7H,8H,9H,9aH,10H,11H,11aH-cyclopenta[a]phenanthren-1-yl}-2-methylhept-2-enoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2E)-6-{3-hydroxy-3a,6,6,9a,11a-pentamethyl-7-oxo-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a]phenanthren-1-yl}-2-methylhept-2-enoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

1-(5,6-dihydroxy-6-methylheptan-2-yl)-3-hydroxy-3a,6,6,9a,11a-pentamethyl-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a]phenanthren-7-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

1-(5,6-dihydroxy-6-methylheptan-2-yl)-3a,6,6,9a,11a-pentamethyl-1H,2H,3H,3aH,5H,5aH,6H,7H,8H,9H,9aH,11H,11aH-cyclopenta[a]phenanthren-7-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(7E)-10-hydroxy-12-(methoxymethyl)-4,8-dimethyl-3,14-dioxatricyclo[9.3.0.0^{2,4}]tetradec-7-en-13-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(2R,3S,4S,5R,6S)-2-(hydroxymethyl)-6-{[4-methyl-1-(propan-2-yl)cyclohex-3-en-1-yl]oxy}oxane-3,4,5-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

3-hydroxy-5-phenylpentanoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

SB-277011 dihydrochloride is a potent, selective, orally bioavailable and brain penetrate antagonist of dopamine D3 receptor(pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively).