T1090

Perphenazine (Trilafon) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.

CWHM-1552 is an effective Plasmodium falciparum inhibitor. For the 3D7 and Dd2 strains, the IC50s are 51 nM and 53 nM.

CXCR2-IN-1 has a pIC50 of 9.3 and is a CXCR2 antagonist of the central nervous system penetration agent.

CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR) alpha. CUDA may be valuable for the study of cardiovascular diseases.

Curcumin-D6 is deuterium-labeled curcumin (Turmeric yellow). Curcumin (T1516) (Turmeric yellow) is a natural phenolic compound with various pharmacological effects, including anti-inflammatory, antioxidant, anti-proliferative and anti-angiogenic activities. Curcumin (T1516) is an inhibitor of p300 histone acetyltransferases (HATs), and also shows inhibitory effects on NF-κB and MAPKs.

CWHM-1008 is an effective oral antimalarial drug. The EC50 values of the drug-sensitive Plasmodium falciparum 3D7 and drug-resistant Dd2 strains are 46 and 21 nM, respectively.

CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting the growth of breast cancer and live

CXCR7 modulator 1 is an effective and orally bioavailable peptoid hybrid CXCR7 modulator with Ki of 9 nM.

CXCR7 modulator 2 is a 7-type C-X-C chemokine receptor (CXCR7) modulator with a Ki of 13 nM.

CY 208-243 is a selective dopamine D1 receptor agonist with anti-Parkinson disease activity.

Cyclic-di-GMP, a STING agonist and ubiquitous second messenger, regulates biofilm formation, motility, and virulence in various bacterial species.

Perphenazine-D4 is a deuterated compound of Perphenazine. Perphenazine (T1090) has a CAS number of 58-39-9. Perphenazine (T1090) is a phenothiazine derivative and a dopamine antagonist with antiemetic and antipsychotic properties.