T1012

Acebutolol hydrochloride (Acebutolol HCl) acts as a cardioselective beta-adrenergic antagonist with little effect on bronchial receptors and has intrinsic sympathomimetic properties. Acebutolol hydrochloride is the hydrochloride salt form of acebutolol, a synthetic butyranilide derivative with hypotensive and antiarrhythmic activity. Having stabilizing and quinidine-like effects on cardiac rhythm, Acebutolol hydrochloride is used in ventricular arrhythmias. Other indications include hypertension, alone or in combinations with other agents.

VEGFR-2-IN-9 (KDR-in-4) is a potent KDR/VEGFR2 inhibitor with an IC50 of 7 nM, suitable for breast cancer research.

Antiulcer Agent 1 is an orally administered derivative of 2-(3,4-dimethoxyphenyl)ethylamine.

(3R,5R)-Rosuvastatin, the (3R,5R)-enantiomer of Rosuvastatin, is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM.

3-Oxo Atorvastatin, an impurity of Atorvastatin, acts as an HMG-CoA reductase inhibitor and effectively decreases blood lipids.

Substance P Receptor Antagonist 1 has potential applications in treating gastrointestinal disorders, inflammatory diseases, respiratory conditions, and central nervous system disorders.

Anti-neurodegeneration agent 1, a neurodegeneration-targeting agent.

(3R,4R)-A2-32-01 is the (R,R)-enantiomer of A2-32-01 and has potential antibacterial activity.

(3S,5R)-Fluvastatin D6 sodium is the deuterium-labeled (3S,5R)-Fluvastatin sodium. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM).

(3S,5R)-Fluvastatin sodium is the enantiomerically pure form of Fluvastatin, a fully synthetic and competitive HMG-CoA reductase inhibitor with nanomolar potency, (3S,5R)-Fluvastatin sodium additionally protects vascular smooth muscle cells from oxidative stress through activation of the Nrf2-dependent antioxidant pathway, supporting cardiovascular and redox biology research.

Apilimod 2HCl (STA 5326 2HCl) is a PIKFYVE kinase inhibitor that promotes NLRP3 inflammatory vesicle activation, IL-1β secretion, and cellular pyroptosis, and is used in the study of amyotrophic lateral sclerosis.